What is PB125?

o   PB125® is a next generation Nrf2 activator, based on our Nrf2.0® Technology

o   It is a potent antioxidant and works by activating/modulating the Nrf2 pathway.

o   It has been shown to combat issues associated with aging and oxidative stress

o   It is a patent-pending, synergistic formulation of naturally-occurring plant-based ingredients

Is PB125 a dietary supplement?

o   PB125® is a dietary supplement that activates the Nrf2 pathway to increase the expression of cell protection mechanisms. 

o   Customers who are pregnant or nursing, and customers with specific health issues should consult with their qualified health care provider prior to taking PB125. 

o   These statements have not been evaluated by the Food and Drug Administration (FDA). PB125 is not intended to diagnose, treat, cure, or prevent any disease.

What is the science behind PB125?

o   Nrf2.0 technology:  product of 15 years+ of research in antioxidants and Nrf2 pathways

o   Enhanced understanding of Nrf2 activation and modulation

o   Multiple scientific studies underway by Pathways Bioscience 

    Click here to learn more about Nrf2 science 

How was PB125 developed?

o   Utilizing Nrf2.0™ Technology, hundreds of natural, plant-based compounds were screened for specific, multi-control-point Nrf2 activation and modulation characteristics.  We sought compounds with demonstrated efficacy, as shown by our own research and published scientific studies.  We paid close attention to safety profiles of compounds — focusing on those with extensive and safe histories of human consumption.

o   Utilized a proprietary model system in the Pathways Bioscience laboratory, we further refined our search for those agents that, when combined, have synergistic Nrf2 activating properties to create the PB dietary supplement series.

o   The optimal combination and composition of PB125 was determined and tested to maximize biological effects and minimize effective dose.

o   Safety was evaluated and validated with internal research, results from other peer-viewed studies, as well as human consumption history. 

o   Modern genomic and proteomic technologies were used to generate gene and protein expression profiles for the ingredients and combinations, which were further analyzed to determine the range of biological effects.

o   Health and wellness benefits of PB125 were assessed by our own research and published scientific studies.

What are the active ingredients in PB125?

o   The major active ingredients are Carnosol,  Withaferin A, and Luteolin.



Where can PB125 be purchased?

o   PB125 is created by and sold only by Pathways Bioscience.

o   A 60-count bottle (60-day supply) of PB125 can be purchased here.



Do you charge sales tax?

o   Only for orders shipping to Colorado addresses (rate = 4.75%).



Do you sell and ship internationally?

o   We do not ship outside of the United States at this time.

o   Please contact us if you have questions.



How is PB125 shipped?

o   Most orders ship by USPS First Class mail, large orders ship by FedEx ground. 



What if I have other questions?

If you have additional questions, please complete our contact form.